Recombinant Mouse Cacna1e Protein, His-tagged

• Cat.No.: Cacna1e-353M
• Product Overview: Recombinant Mouse Cacna1e Protein (Gly246-Trp327) with N-His tag was expressed in E. coli.

Specification

• Description: This gene encodes an integral membrane protein that belongs to the calcium channel alpha-1 subunits family. Voltage-sensitive calcium channels mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes. Voltage-dependent calcium channels are multi-subunit complexes, comprised of alpha-1, alpha-2, beta and delta subunits in a 1:1:1:1 ratio. The isoform alpha-1E gives rise to R-type calcium currents and belongs to the high-voltage activated group. Calcium channels containing the alpha-1E subunit may be involved in the modulation of neuronal firing patterns, an important component of information processing.
• Source: E. coli
• Species: Mouse
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 39 kDa
  Accurate Molecular Mass: 42 kDa
• Protein length: Gly246-Trp327
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1 mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: Cacna1e calcium channel, voltage-dependent, R type, alpha 1E subunit [ Mus musculus (house mouse) ]
• Official Symbol: Cacna1e
• Synonyms: CACNA1E; calcium channel, voltage-dependent, R type, alpha 1E subunit; voltage-dependent R-type calcium channel subunit alpha-1E; brain calcium channel II; voltage-gated calcium channel subunit alpha Cav2.3; calcium channel, L type, alpha-1 polypeptide, isoform 6; calcium channel, voltage-dependent, L type, alpha 1E subunit; BII; Cach6; Cav2.3; Cchra1; alpha1E; Cacnl1a6; A430040I15
• Gene ID: 12290
• mRNA Refseq: NM_009782
• Protein Refseq: NP_033912
• UniProt ID: A0A087WS83