Recombinant Mouse Bad Protein, MYC/DDK-tagged

• Cat.No.: Bad-689M
• Product Overview: Purified recombinant protein of full-length mouse BCL2-associated agonist of cell death (Bad), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 22.1 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Bad BCL2-associated agonist of cell death [ Mus musculus (house mouse) ]
• Official Symbol: Bad
• Synonyms: Bad; BCL2-associated agonist of cell death; Bbc2; AI325008; bcl2-associated agonist of cell death; bcl-2-binding component 6; bcl-xL/Bcl-2-associated death promoter; bcl2 antagonist of cell death
• Gene ID: 12015
• mRNA Refseq: NM_007522
• Protein Refseq: NP_031548
• UniProt ID: Q61337