Recombinant Mouse Atp7b Protein, His-tagged

• Cat.No.: Atp7b-275M
• Product Overview: Recombinant Mouse Atp7b Protein (Gln1369-Ile1462) with N-His tag was expressed in E. coli.

Specification

• Species: Mouse
• Source: E.coli
• Tag: His
• Protein Length: Gln1369-Ile1462
• Description: Enables P-type divalent copper transporter activity. Acts upstream of or within several processes, including cellular transition metal ion homeostasis; lactation; and protein maturation by copper ion transfer. Located in membrane and trans-Golgi network. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Used to study Wilson disease. Human ortholog(s) of this gene implicated in Wilson disease. Orthologous to human ATP7B (ATPase copper transporting beta).
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 14.3 kDa
  Accurate Molecular Mass: 14 kDa
• Purity: > 97%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: Atp7b ATPase, Cu++ transporting, beta polypeptide [ Mus musculus (house mouse) ]
• Official Symbol: Atp7b
• Synonyms: ATP7B; ATPase, Cu++ transporting, beta polypeptide; copper-transporting ATPase 2; toxic milk; copper pump 2; Wilson protein; wilson disease-associated protein homolog; tx; WND; Atp7a
• Gene ID: 11979
• mRNA Refseq: NM_007511
• Protein Refseq: NP_031537
• UniProt ID: Q64446