Recombinant Mouse ATP1b1, His-tagged

• Cat.No.: ATP1b1-3766M
• Product Overview: ATPase, Na+/K+ Transporting Beta 1 Polypeptide (ATP1b1)

Specification

• Description: This gene encodes an integral membrane protein that comprises a subunit of an ATP-metabolizing enzyme responsible for transporting sodium and potassium ions across the plasma membrane. This enzyme regulates the electrochemical gradient of these ions in cells, and plays a central role in osmoregulation and signal transmission in nerves and muscles, among other biological processes. The encoded protein is the non-catalytic beta subunit; it works together with a catalytic alpha subunit and a gamma subunit.
• Source: E. Coli
• Species: Mouse
• Tag: His
• Form: Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Molecular Mass: 30.7kDa
• Protein length: 304
• Endotoxin: <1.0eu per 1ug (determined by the lal</1.0eu
• Purity: >95%
• Applications: SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
• Notes: Small volumes of ATP1b1 recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Warning: This product is for research use only. Not for use in diagnostic or therapeutic procedures.

Gene Information

• Gene Name: Atp1b1 ATPase, Na+/K+ transporting, beta 1 polypeptide [ Mus musculus ]
• Official Symbol: ATP1b1
• Synonyms: ATP1B1; ATPase, Na+/K+ transporting, beta 1 polypeptide; sodium/potassium-transporting ATPase subunit beta-1; sodium/potassium ATPase beta subunit; sodium/potassium-dependent ATPase subunit beta-1; Atpb; Atpb-1
• Gene ID: 11931
• mRNA Refseq: NM_009721
• Protein Refseq: NP_033851
• Chromosome Location: 1 H2.2; 1 71.75 cM
• Pathway: Aldosterone-regulated sodium reabsorption, organism-specific biosystem; Aldosterone-regulated sodium reabsorption, conserved biosystem; Basigin interactions, organism-specific biosystem; Bile secretion, organism-specific biosystem; Bile secretion, conserv
• Function: protein binding; sodium:potassium-exchanging ATPase activity