Recombinant Mouse Atg5 Protein, MYC/DDK-tagged

• Cat.No.: Atg5-624M
• Product Overview: Purified recombinant protein of full-length mouse autophagy related 5 (Atg5), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Two transcript variants encoding different protein isoforms have been found for this gene.
• Molecular Mass: 32.4 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Atg5 autophagy related 5 [ Mus musculus (house mouse) ]
• Official Symbol: Atg5
• Synonyms: Atg5; autophagy related 5; Apg5l; Atg5l; Paddy; C88337; AW319544; 2010107M05Rik; 3110067M24Rik; autophagy protein 5
• Gene ID: 11793
• mRNA Refseq: NM_053069
• Protein Refseq: NP_444299
• UniProt ID: Q99J83