Recombinant Mouse Arpc3 Protein, Myc/DDK-tagged

• Cat.No.: Arpc3-1726M
• Product Overview: Purified recombinant protein of mouse full-length actin related protein 2/3 complex, subunit 3 (Arpc3), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA. The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs).
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 20.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Arpc3 actin related protein 2/3 complex, subunit 3 [ Mus musculus (house mouse) ]
• Official Symbol: Arpc3
• Synonyms: ARPC3; actin related protein 2/3 complex, subunit 3; actin-related protein 2/3 complex subunit 3; p21-ARC; arp2/3 complex 21 kDa subunit; Arp2/3 complex subunit p21-Arc; 21kDa; p21-Ar; p21Arc; AA408672; AI788639; 1110006A04Rik
• Gene ID: 56378
• mRNA Refseq: NM_019824
• Protein Refseq: NP_062798
• UniProt ID: Q9JM76