ARPC3

  • Official Full Name

    actin related protein 2/3 complex, subunit 3, 21kDa

  • Overview

    This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p21 subunit, has yet to be determined.

  • Synonyms

    ARPC3;actin related protein 2/3 complex, subunit 3, 21kDa;actin related protein 2/3 complex, subunit 3 (21 kD);actin-related protein 2/3 complex subunit 3;ARC21;p21 Arc;Actin related protein 2/3 complex subunit 3;ARP2/3 complex 21 kDa subunit;ARP2/3 protein complex subunit p21;p21-Arc

Recombinant Proteins

  • Human
  • Mouse
  • Zebrafish
  • Rhesus macaque
  • Chicken
  • E.coli
  • Mammalian Cell
  • Wheat Germ
  • HEK293
  • In Vitro Cell Free System
  • Human Cells
  • HEK293T
  • GST
  • His
  • Non
  • Myc&DDK
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
ARPC3-9884H Recombinant Human ARPC3, GST-tagged E.coli Human GST 1-178a.a.
ARPC3-1968M Recombinant Mouse ARPC3 Protein Mammalian Cell Mouse His
ARPC3-342Z Recombinant Zebrafish ARPC3 Mammalian Cell Zebrafish His
ARPC3-417R Recombinant Rhesus monkey ARPC3 Protein, His-tagged Mammalian Cell Rhesus macaque His
ARPC3-4880C Recombinant Chicken ARPC3 Mammalian Cell Chicken His
ARPC3-7591H Recombinant Human ARPC3, His-tagged E.coli Human His 1-178aa
ARPC3-847H Recombinant Human ARPC3 protein, GST-tagged Wheat Germ Human GST
ARPC3-37HCL Recombinant Human ARPC3 lysate HEK293 Human Non
ARPC3-1101HF Recombinant Full Length Human ARPC3 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 178 amino acids
ARPC3-151H Recombinant Human ARPC3 Protein, His-tagged Human Cells Human His
Arpc3-1726M Recombinant Mouse Arpc3 Protein, Myc/DDK-tagged HEK293T Mouse Myc&DDK
ARPC3-246R Recombinant Rhesus Macaque ARPC3 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
ARPC3-246R-B Recombinant Rhesus Macaque ARPC3 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
ARPC3-2793H Recombinant Human ARPC3 Protein, MYC/DDK-tagged HEK293 Human Myc&DDK
ARPC3-5195H Recombinant Human ARPC3 protein, GST-tagged E.coli Human GST 2-175aa
ARPC3-5659H Recombinant Human ARPC3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Human Myc&DDK
ARPC3-749M Recombinant Mouse ARPC3 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
ARPC3-749M-B Recombinant Mouse ARPC3 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    ARPC3 involved in several pathways and played different roles in them. We selected most pathways ARPC3 participated on our site, such as Axon guidance,B Cell Receptor Signaling Pathway,Bacterial invasion of epithelial cells, which may be useful for your reference. Also, other proteins which involved in the same pathway with ARPC3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    EPH-Ephrin signaling EFNA5,ARPC4,ACTR2B,ITSN1,EPHA2A,AP2S1,KALRN,AP2B1,AP2A2,EPHA4A
    Developmental Biology MED23,EBF1,EFNA2A,CAP2,PAK4,POU5F3,DUSP5,EFNA5,KLB,RASGRP4
    EPHB-mediated forward signaling EFNB3,ARPC1A,ACTR3,ITSN1,EPHB4A,ACTR2,ARHGEF28,KALRN,ARPC5,EFNB2
    CDC42 signaling events ACTR3,IQGAP3,TNK2,ARPC5,EPS8,CFL1,PAK4,ACTR2,ARPC1B,BAIAP2
    Endocytosis IST1,CAV3,ARFGEF1,SH3GL3A,ACAP1,RAB35,ADRBK2,CHMP6,FOLR3,CHMP7
    Axon guidance AP2A1,NFATC4,AP2S1,AP2A2,COL6A3,GSK3B,SCN3A,RGMB,PAK6,NRP1A
    Bacterial invasion of epithelial cells SHC3,MET,ITGB1,PIK3CD,CBL,PIK3CB,CDC42,ELMO3,CDH1,ELMO2
    B Cell Receptor Signaling Pathway ARPC1B, Cd79b,PTPN6,BLNK,IKBKG,MALT1,PILRB,FCGR2B,DUSP4,NFATC2

    Protein Function

    ARPC3 has several biochemical functions, for example, contributes_to actin filament binding,protein binding,structural constituent of cytoskeleton. Some of the functions are cooperated with other proteins, some of the functions could acted by ARPC3 itself. We selected most functions ARPC3 had, and list some proteins which have the same functions with ARPC3. You can find most of the proteins on our site.

    Function Related Protein
    structural constituent of cytoskeleton BFSP1,TUBA8L2,GFAP,DSP,SPTBN1,KRT2,TUBA1B,ACTR2,COX4I2,EPB41L3
    contributes_to actin filament binding ARPC5,MYH10,ACTR3,ARPC2,ARPC4,MYH9,ARPC1B,ACTR2
    protein binding IMP3,TRAPPC6A,ARNT,NMNAT1,OSBPL1A,USO1,HIST1H1A,FAM64A,TCF25,PAK1

    Interacting Protein

    ARPC3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARPC3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ARPC3.

    WASL;HOXA3;NRIP1;GOLGA2;VCAM1;Ptms;ACTR3B;LTA4H;CETP

    Resources

    References

    • Schmidt, S; Willers, J; et al. Effect of omega-3 polyunsaturated fatty acids on the cytoskeleton: an open-label intervention study. LIPIDS IN HEALTH AND DISEASE 14:-(2015).
    • Yang, WL; Thein, S; et al. Arp2/3 complex regulates adipogenesis by controlling cortical actin remodelling. BIOCHEMICAL JOURNAL 464:179-192(2014).

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