Recombinant Mouse Arfip2 Protein, Myc/DDK-tagged

• Cat.No.: Arfip2-1676M
• Product Overview: Purified recombinant protein of mouse full-length ADP-ribosylation factor interacting protein 2 (Arfip2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Plays a role in constitutive metalloproteinase (MMP) secretion from the trans Golgi network. May have important functions during vesicle biogenesis at certain cargo subdomains, which could be predominantly utilized by secreted MMPs, such as MMP7 and MMP2. Participates also in autophagy by regulating the starvation-depdendent trafficking of ATG9A vesicles which deliver the PI4-kinase to the autophagosome initiation site. In addition, plays a role in NF-kappa-B inhibition by interacting with IKBKB and IKBKG.
• Molecular Mass: 37.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Arfip2 ADP-ribosylation factor interacting protein 2 [ Mus musculus (house mouse) ]
• Official Symbol: Arfip2
• Synonyms: ARFIP2; ADP-ribosylation factor interacting protein 2; arfaptin-2; Arfaptin 2; partner of RAC1; ADP-ribosylation factor-interacting protein 2; POR; Por1; 2310002N04Rik
• Gene ID: 76932
• mRNA Refseq: NM_029802
• Protein Refseq: NP_084078
• UniProt ID: Q8K221