Recombinant Mouse Anapc11 Protein, Myc/DDK-tagged

• Cat.No.: Anapc11-1620M
• Product Overview: Purified recombinant protein of mouse full-length anaphase promoting complex subunit 11 (Anapc11), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Together with the cullin protein ANAPC2, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.
• Molecular Mass: 9.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Anapc11 anaphase promoting complex subunit 11 [ Mus musculus (house mouse) ]
• Official Symbol: Anapc11
• Synonyms: ANAPC11; anaphase promoting complex subunit 11; anaphase-promoting complex subunit 11; APC11; cyclosome subunit 11; anaphase promoting complex subunit 11 homolog; R75218; 1110011I19Rik
• Gene ID: 66156
• mRNA Refseq: NM_025389
• Protein Refseq: NP_079665
• UniProt ID: Q9CPX9