Recombinant Mouse Aktip Protein, Myc/DDK-tagged

• Cat.No.: Aktip-1587M
• Product Overview: Purified recombinant protein of mouse full-length thymoma viral proto-oncogene 1 interacting protein (Aktip), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Regulates apoptosis by enhancing phosphorylation and activation of AKT1. Increases release of TNFSF6 via the AKT1/GSK3B/NFATC1 signaling cascade.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 32.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Aktip AKT interacting protein [ Mus musculus (house mouse) ]
• Official Symbol: Aktip
• Synonyms: AKTIP; thymoma viral proto-oncogene 1 interacting protein; AKT-interacting protein; fused toes protein; Ft; Fif; Ft1; Fts; AL023020
• Gene ID: 14339
• mRNA Refseq: NM_010241
• Protein Refseq: NP_034371
• UniProt ID: Q64362