Recombinant Mouse Adam11 Protein, MYC/DDK-tagged

• Cat.No.: Adam11-534M
• Product Overview: Purified recombinant protein of full-length mouse a disintegrin and metallopeptidase domain 11 (Adam11), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: This gene encodes a member of a disintegrin and metalloprotease (ADAM) family of endoproteases that play important roles in various biological processes including cell signaling, adhesion and migration. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional protein. The protein encoded by this gene is believed to lack metalloproteinase activity due to the lack of a critical catalytic motif. Mice lacking the encoded protein exhibit defects in spatial learning, motor coordination and altered perception of pain. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 84.6 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Adam11 a disintegrin and metallopeptidase domain 11 [ Mus musculus (house mouse) ]
• Official Symbol: Adam11
• Synonyms: Adam11; a disintegrin and metallopeptidase domain 11; Mdc; AW060611; disintegrin and metalloproteinase domain-containing protein 11; a disintegrin and metalloprotease domain (ADAM) 11; metalloproteinase-like, disintegrin-like, and cysteine-rich protein
• Gene ID: 11488
• mRNA Refseq: NM_009613
• Protein Refseq: NP_033743
• UniProt ID: Q9R1V4