Recombinant Human ZKSCAN3 Protein, MYC/DDK-tagged

• Cat.No.: ZKSCAN3-09H
• Product Overview: Recombinant protein of human zinc finger with KRAB and SCAN domains 3 (ZKSCAN3) with a C-Myc/DDK tag was expressed in HEK293T.

Specification

• Description: Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migration in various tumors and myelomas.
• Source: HEK293T
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 60.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 μ/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Gene Information

• Gene Name: ZKSCAN3 zinc finger with KRAB and SCAN domains 3 [ Homo sapiens (human) ]
• Official Symbol: ZKSCAN3
• Synonyms: ZKSCAN3; zinc finger with KRAB and SCAN domains 3; ZF47; Zfp47; ZFP306; ZNF306; ZNF309; zfp-47; ZSCAN13; ZSCAN35; dJ874C20.1; dJ874C20.1; zinc finger protein with KRAB and SCAN domains 3; zinc finger and SCAN domain-containing protein 13; zinc finger protein 306; zinc finger protein 309; zinc finger protein 47 homolog; zinc finger protein zfp47
• Gene ID: 80317
• mRNA Refseq: NM_024493
• Protein Refseq: NP_077819
• MIM: 612791
• UniProt ID: Q9BRR0