ZKSCAN3
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Official Full Name
zinc finger with KRAB and SCAN domains 3 -
Synonyms
ZKSCAN3;zinc finger with KRAB and SCAN domains 3;zinc finger protein 306 , zinc finger protein 309 , ZNF306, ZNF309;zinc finger protein with KRAB and SCAN domains 3;dJ874C20.1;ZF47;Zfp47;mszf35;SCAN-KRAB-zinc finger protein;Skz1;Zfp-47;ZFP306;Zfp307;Zinc finger and SCAN domain containing protein 13;Zinc finger and SCAN domain-containing protein 13;Zinc finger protein 306;Zinc finger protein 306, isoform CRA_a;Zinc finger protein 307;Zinc finger protein 309;Zinc finger protein 47 homolog;Zinc finger protein with KRAB and SCAN domains3;Zinc finger protein zfp47;ZKSC3_HUMAN;ZNF309;ZSCAN13;OTTHUMP00000016204;ZNF306;dJ874C20.1.
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ZKSCAN3-2005HCL | Recombinant Human ZKSCAN3 cell lysate | Human | Non |
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| ZKSCAN3-09H | Recombinant Human ZKSCAN3 Protein, MYC/DDK-tagged | HEK293 | Human | DDK&Myc |
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| ZKSCAN3-1789H | Recombinant Human ZKSCAN3 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | DDK&Myc |
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Involved Pathway
ZKSCAN3 involved in several pathways and played different roles in them. We selected most pathways ZKSCAN3 participated on our site, such as Gene Expression,Generic Transcription Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ZKSCAN3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Generic Transcription Pathway | ZNF561,ZFP37,ZNF498,MED25,MED6,NRBF2,NR1I3,ZFP90,ZNF445,ZNF3 |
| Gene Expression | ZNF486,NR1D2B,ZNF791,PUS1,CDK9,POP4,RARAB,NR5A1,NR2C2,Txn1 |
Protein Function
ZKSCAN3 has several biochemical functions, for example, DNA binding,RNA polymerase II core promoter proximal region sequence-specific DNA binding,chromatin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ZKSCAN3 itself. We selected most functions ZKSCAN3 had, and list some proteins which have the same functions with ZKSCAN3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA polymerase II core promoter proximal region sequence-specific DNA binding | EP300,JUNB,GLI3,CC2D1B,FOSL1,CHD7,FOXD1,HOXC11,TCF3,ARID3B |
| DNA binding | OVOL2,ISX,MSH2,ZNF829,RPS3,PRRX1A,OTUD7A,CCDC79,CREM,YBX1 |
| transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding | TBX15,ETS2,PITX2,PRDM5,CC2D1B,IFI16,SKIL,ZNF217,CTCF,BCL11AA |
| metal ion binding | CDK2,NT5C2L1,TRAF4A,ZIC3,PAPD7,MAP3K2,JMJD5,PPARAB,PRDM16,CYP17A2 |
| chromatin binding | WHSC1,HINFP,APTX,CHD8,ATF5,NSBP1,TRP63,LDB1,SKOR2,ZGLP1 |
| transcription factor activity, sequence-specific DNA binding | TRERF1,TFDP1A,WT1B,HSFY1,ZFP629,RXRBA,MYCN,MNT,ZNF83,TBPL2 |
| sequence-specific DNA binding | FOXH1,RHOXF2,NKX3-1,NR2E3,IRX4,ATF4B2,ZNF397,NKX2-5,ISL1L,HOXB2A |
| protein binding | PKD2L1,VPS16,PSMB5,CLASP1,MAGEA9,SH3PXD2A,RBX1,TPSAB1,TTC39B,GRIA2 |
Interacting Protein
ZKSCAN3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ZKSCAN3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ZKSCAN3.
LZTS2;GRB2
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References
- Yang, L; Hamilton, SR; et al. The previously undescribed ZKSCAN3 (ZNF306) is a novel "driver" of colorectal cancer progression. CANCER RESEARCH 68:4321-4330(2008).
