Recombinant Human Zinc Finger Protein 395, T7-tagged

• Cat.No.: ZNF395-3018H
• Product Overview: Recombinant Human ZNF395 protein was expressedwith N-terminal T7-tag inE.coliand purified by using conventional chromatography techniques, 54.9kDa (513aa).

Specification

• Cat. No.: ZNF395-3018H
• Description: Zinc finger protein 395 is a novel transcription factor shuttling between nucleus and cytoplasm and bind to the specific GCCGGCG, which is an essential cis-element for HD gene expression in neuronal cells. ZNF395 can interact with repression-mediating E2 binding site P2 of human papillomavirus type 8 (HPV8) and play a role in transcription of PV genes and in E2-me.
• Sequences of amino acids: MASVLSRRLG KRSLLGARVL GPSASEGPSA APPSEPLLEG AAPQPFTTSD DTPCQEQPKE VLKAPSTSGL QQVAFQPGQK VYVWYGGQEC TGLVEQHSWM EGQVTVWLLE QKLQVCCRVE EVWLAELQGP CPQAPPLEPG AQALAYRPVS RNIDVPKRKS DAVEMDEMMA AMVLTSLSCS PVVQSPPGTE ANFSASRAAC DPWKESGDIS DSGSSTTSGH WSGSSGVSTP SPPHPQASPK YLGDAFGSPQ TDHGFETDPD PFLLDEPAPR KRKNSVKVMY KCLWPNCGKV LRSIVGIKRH VKALHLGDTV DSDQFKREED FYYTEVQLKE ESAAAAAAAA AGTPVPGTPT SEPAPTPSMT GLPLSALPPP LHKAQSSGPE HPGPESSLPS GALSKSAPGS FWHIQADHAY QALPSFQIPV SPHIYTSVSW AAAPSAACSL SPVRSRSLSF SEPQQPAPAM KSHLIVTSPP RAQSGARKAR GEAKKCRKVY GIEHRDQWCT ACRWKKACQR FLD
• Formulation: 10 mM Tris pH 8.0. 0.1% Triton X-100. 0.002% NaN3.
• Purity: > 95% by SDS - PAGE

Gene Information

• Gene Name: ZNF395 zinc finger protein 395 [ Homo sapiens ]
• Synonyms: DKFZp434K1210; HDBP2; HDBP-2; HD gene regulatory region-binding protein 2; HD-regulating factor 2; HDRF-2; Huntington disease gene regulatory region-binding protein 2; Papillomavirus-binding factor; Papillomavirus regulatory factor 1; PBF; PRF1; PRF-1; Si-1-8-14; ZNF395; Zinc finger protein 395
• Gene ID: 55893
• mRNA Refseq: NM_018660
• Protein Refseq: NP_061130
• MIM: 609494
• UniProt ID: Q9H8N7
• Chromosome Location: 8p21.1
• Function: DNA binding; DNA-dependent zinc ion binding; intracellular nucleus cytoplasm regulation of transcription; plays a role in papillomavirus genes transcription; metal ion binding