Recombinant Human ZBTB7B, His-tagged

• Cat.No.: ZBTB7B-29517TH
• Product Overview: Recombinant full length Human ThPOK with a C-terminal His-tag, 90 kDa.

Specification

• Description: This gene encodes a zinc finger-containing transcription factor that acts as a key regulator of lineage commitment of immature T-cell precursors. It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. It also functions as a transcriptional repressor of type I collagen genes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Protein length: 539 amino acids
• Conjugation: HIS
• Molecular Weight: 90.000kDa inclusive of tags
• Source: E. coli
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 55mM Tris HCl, 150mM Sodium chloride, pH 8.2
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Sequence Similarities: Contains 1 BTB (POZ) domain.Contains 4 C2H2-type zinc fingers.

Gene Information

• Gene Name: ZBTB7B zinc finger and BTB domain containing 7B [ Homo sapiens ]
• Official Symbol: ZBTB7B
• Synonyms: ZBTB7B; zinc finger and BTB domain containing 7B; ZFP67, zinc finger protein 67 homolog (mouse); zinc finger and BTB domain-containing protein 7B; c Krox; hcKrox; ZBTB15; zinc finger and BTB domain containing 15; ZNF857B
• Gene ID: 51043
• mRNA Refseq: NM_001252406
• Protein Refseq: NP_001239335
• MIM: 607646
• Uniprot ID: O15156
• Chromosome Location: 1q21.2
• Function: DNA binding; metal ion binding; zinc ion binding