Recombinant Human YWHAH Protein, GST-tagged

• Cat.No.: YWHAH-143H
• Product Overview: Recombinant Human YWHAH fused with GST tag at N-terminal was expressed in Insect cells.

Specification

• Description: 14-3-3 eta (also known as tyrosine 3-monooxygenase/ tryptophan 5-monooxygenase activation protein, eta polypeptide) plays a key role in tissue differentiation in neural development and in early mesenchyme. The 14-3-3 eta protein belongs to family of acidic proteins present exclusively in the brain and is believed to have a function in monoamine biosynthesis. 14-3-3 eta protein regulates human tyrosine hydroxylase type 1 (hTH1) stability by acting on the N-terminus. 14-3-3 eta can bind to parkin, which encodes an E3 ubiquitin-protein ligase, in the linker region and negatively regulate its ubiquitin ligase activity.
• Source: E. coli
• Species: Human
• Tag: GST
• Form: 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol
• Molecular Mass: 55 kDa
• Purity: > 95%
• Applications: Western Blot
• Stability: 1 year at -70 centigrade from date of shipment.
• Storage: Store product at –70centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.2 ug/ml

Gene Information

• Gene Name: YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide [ Homo sapiens ]
• Official Symbol: YWHAH
• Synonyms: YWHAH; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide; YWHA1; 14-3-3 protein eta; 14 3 3 eta; 14-3-3 eta
• Gene ID: 7533
• mRNA Refseq: NM_003405
• Protein Refseq: NP_003396
• MIM: 113508
• UniProt ID: Q04917