Recombinant Human YWHAG Protein, His-tagged

• Cat.No.: YWHAG-144H
• Product Overview: Recombinant Human YWHAG fused with His tag at N-terminal was expressed in Insect cells.

Specification

• Species: Human
• Source: Insect Cells
• Tag: His
• Description: 14-3-3 gamma (also known as tyrosine 3-monooxygenase/tryp-tophan 5-monooxygenase activation protein, gamma polypeptide) is a member of the 14-3-3 family and is involved in mediating signal transduction by binding to phosphoserine-containing proteins. 14-3-3 gamma can interact with various signaling components including RAF1 and protein kinase C. Various growth factors can induce expression of 14-3-3 gamma in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. Upregulation of 14-3-3 gamma plays a specific protective role in astrocytes under ischemia. Elevation of 14-3-3 gamma protein in astrocytes promotes survival, while a decrease in 14-3-3 gamma enhances apoptosis in astrocytes under ischemia.
• Form: 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol
• Molecular Mass: 32 kDa
• Purity: > 90%
• Applications: Western Blot
• Stability: 1 year at -70 centigrade from date of shipment.
• Storage: Store product at –70centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.2 ug/ml

Gene Information

• Gene Name: YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide [ Homo sapiens ]
• Official Symbol: YWHAG
• Synonyms: YWHAG; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide; 14-3-3 protein gamma; 14 3 3 gamma; KCIP-1; 14-3-3 gamma; protein kinase C inhibitor protein 1; 14-3-3GAMMA
• Gene ID: 7532
• mRNA Refseq: NM_012479
• Protein Refseq: NP_036611
• MIM: 605356
• UniProt ID: P61981