Recombinant Human Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein, Gamma Polypeptide

• Cat.No.: YWHAG-6934H
• Product Overview: Recombinant human YWHAG was expressed in E. coli and purified by using conventional chromatography techniques. MW: 28 kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Protein Length: 1-247aa
• Description: The 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. The YWHAG, a subtype of the 14-3-3 family of proteins, was thought to be brain and neuron-specific.
• Form: Liquid in 20mM Tris (pH 7.4).
• Molecular Mass: 28 kDa (247 aa), confirmed by MALDI-TOF.
• AA Sequence: MVDREQLVQK ARLAEQAERY DDMAAAMKNV TELNEPLSNE ERNLLSVAYK NVVGARRSSW RVISSIEQKT SADGNEKKIE MVRAYREKIE KELEAVCQDV LSLLDNYLIK NCSETQYESK VFYLKMKGDY YRYLAEVATG EKRATVVESS EKAYSEAHEI SKEHMQPTHP IRLGLALNYS VFYYEIQNAP EQACHLAKTA FDDAIAELDT LNEDSYKDST LIMQLLRDNL TLWTSDQQDD DGGEGNN
• Endotoxin: < 1.0 eu per 1 ug of protein (determined by lal
• Purity: >95% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide [ Homo sapiens ]
• Official Symbol: YWHAG
• Synonyms: YWHAG; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide; 14-3-3 protein gamma; 14 3 3 gamma; KCIP-1; 14-3-3 gamma; protein kinase C inhibitor protein 1; 14-3-3GAMMA
• Gene ID: 7532
• mRNA Refseq: NM_012479
• Protein Refseq: NP_036611
• MIM: 605356
• UniProt ID: P61981
• Chromosome Location: 7q11.23
• Pathway: Calcium Regulation in the Cardiac Cell, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, conserved biosystem; Centrosome maturation, organism-specific biosystem
• Function: insulin-like growth factor receptor binding; protein binding; protein domain specific binding; protein kinase C binding; protein kinase C inhibitor activity; receptor tyrosine kinase binding