Recombinant Human WWP2 Protein, MYC/DDK-tagged

• Cat.No.: WWP2-376H
• Product Overview: Recombinant human WWP2 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Description: This gene encodes a member of the Nedd4 family of E3 ligases, which play an important role in protein ubiquitination. The encoded protein contains four WW domains and may play a role in multiple processes including chondrogenesis and the regulation of oncogenic signaling pathways via interactions with Smad proteins and the tumor suppressor PTEN. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 10. [provided by RefSeq, Jul 2012]
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 35.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: WW domain containing E3 ubiquitin protein ligase 2 [ Homo sapiens ]
• Official Symbol: WWP2
• Synonyms: AIP2; WWp2-like
• Gene ID: 11060
• mRNA Refseq: NM_007014.3
• Protein Refseq: NP_008945.2
• MIM: 602308
• UniProt ID: O00308