Recombinant Human Within Bgcn Homolog (Drosophila), His-tagged

• Cat.No.: WIBG-2771H
• Product Overview: Recombinant human WIBG protein, fused to His-tag at C-terminus, was expressed inE.coliand purified by using conventional chromatography techniques. MW = 23.7kDa (212aa).

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: WIBG has been identified as an interacting partner of Mago-Y14. The Mago-Y14 heterodimer is a core component of the EJC(exon junction complex) that is deposited on mRNAs as a consequence of splicing and influences postsplicing mRNA metabolism. This protein is a cytoplasmic RNA-binding protein that is excluded from the nucleus by Crm1. It interacts directly with Mago-Y14 by means of its N-terminal domain.
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.1M NaCl.
• Purity: > 85% by SDS - PAGE.
• Concentration: 0.5 mg/ml (determined by Bradford assay).
• Sequences Of Amino Acids: MEAAGSPAAT ETGKYIASTQ RPDGTWRKQR RVKEGYVPQE EVPVYENKYV KF FKSKPELP PGLSPEATAP VTPSRPEGGE PGLSKTAKRNLKRKEKRRQQ QEK GE AEALS RTLDKVSLEE TAQLPSAPQG SRAAPTAASD QPDSAATTEK AKKIKNLKKK LRQVEELQQR IQAGEVSQPS KEQLEKLARR RALEEELEDL ELGLLEHHHH HH.
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: WIBG within bgcn homolog (Drosophila) [ Homo sapiens ]
• Synonyms: within bgcn homolog (Drosophila); PYM; MGC13064; WIBG; 12q13.2; partner of Y14 and mago; protein wibg homolog; Protein wibg homolog
• Gene ID: 84305
• mRNA Refseq: NM_001143853
• Protein Refseq: NP_001137325
• UniProt ID: Q9BRP8
• Chromosome Location: 12q13.2
• Function: RNA binding; protein binding; ribosome binding