Recombinant Human VBP1, His-tagged

• Cat.No.: VBP1-7079H
• Product Overview: Recombinant human VBP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Description: Prefoldin subunit 3, also known as VBP1, belongs to the prefoldin subunit alpha family. VBP1 interacts with the Von Hippel-Lindau protein to form an intracellular complex. Because it functions as a chaperone protein, it is suspected that it may play a role in the transport of the Von Hippel-Lindau protein from the perinuclear granules to the nucleus or cytoplasm.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl,50% glycerol,2mM DTT
• Molecular Mass: 25 kDa (220aa)
• Protein length: 1-197aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMAAVKDS CGKGEMATGN GRRLHLGIPE AVFVEDVDSF MKQPGNETAD TVLKKLDEQY QKYKFMELNLAQKKRRLKGQ IPEIKQTLEI LKYMQKKKES TNSMETRFLL ADNLYCKASV PPTDKVCLWL GANVMLEYDI DEAQALLEKN LSTATKNLDS LEEDLDFLRD QFTTTEVNMA RVYNWDVKRR NKDDSTKNKA
• Purity: >90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml

Gene Information

• Gene Name: VBP1 von Hippel-Lindau binding protein 1 [ Homo sapiens ]
• Official Symbol: VBP1
• Synonyms: VBP1; von Hippel-Lindau binding protein 1; prefoldin subunit 3; PFD3; PFDN3; prefoldin 3; HIBBJ46; VHL binding protein-1; VHL-binding protein 1; von Hippel-Lindau-binding protein 1; VBP-1
• Gene ID: 7411
• mRNA Refseq: NM_003372
• Protein Refseq: NP_003363
• MIM: 300133
• UniProt ID: P61758
• Chromosome Location: Xq28
• Pathway: Chaperonin-mediated protein folding, organism-specific biosystem; Cooperation of Prefoldin and TriC/CCTin actin and tubulin folding, organism-specific biosystem; Metabolism of proteins, organism-specific biosystem; Prefoldin mediated transfer of substrateto CCT/TriC, organism-specific biosystem; Protein folding, organism-specific biosystem
• Function: unfolded protein binding