VBP1
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Official Full Name
von Hippel-Lindau binding protein 1 -
Overview
The protein encoded by this gene interacts with the Von Hippel-Lindau protein to form an intracellular complex.Because it functions as a chaperone protein, it is suspected that it may play a role in the transport of the Von Hippel-Lindau protein from the perinuclear granules to the nucleus or cytoplasm. -
Synonyms
VBP1;von Hippel-Lindau binding protein 1;prefoldin subunit 3;PFD3;PFDN3;prefoldin 3;HIBBJ46;VHL binding protein-1;VHL-binding protein 1;von Hippel-Lindau-binding protein 1;VBP-1
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| VBP1-3654H | Recombinant Human VBP1, His-tagged | E.coli | Human | His | 1-197aa | |
| VBP1-2799Z | Recombinant Zebrafish VBP1 | Mammalian Cell | Zebrafish | His |
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| VBP1-7079H | Recombinant Human VBP1, His-tagged | E.coli | Human | His | 1-197aa |
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| VBP1-420HCL | Recombinant Human VBP1 293 Cell Lysate | HEK293 | Human | Non |
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| VBP1-5875H | Recombinant Human VBP1 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| Vbp1-6908M | Recombinant Mouse Vbp1 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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Involved Pathway
VBP1 involved in several pathways and played different roles in them. We selected most pathways VBP1 participated on our site, such as Chaperonin-mediated protein folding,Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding,Metabolism of proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with VBP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Protein folding | PFDN1,PFDN2,FBXW2,TBCA,FKBP9,TBCC,NOP56,TBCD,ARL2,PFDN4 |
| Metabolism of proteins | IGFBP2B,NEU4,CGB5,SFTPB,MUC1,MUC15,TOMM6,HYOU1,TRAPPC9,SUMF2 |
| Chaperonin-mediated protein folding | FBXW4,TUBA1B,FBXL5,CCT7,FBXW9,TUBA3D,TCP1,FKBP9,FBXW5,NOP56 |
| Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding | PFDN4,CCT8,CCT6A,TUBA1B,CCT5,TUBB4B,TCP1,PFDN6,PFDN5,CCT3 |
| Prefoldin mediated transfer of substrate to CCT/TriC | CCT6A,PFDN6,PFDN2,PFDN5,CCT7,PFDN1,PFDN4 |
Protein Function
VBP1 has several biochemical functions, for example, protein binding,tubulin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by VBP1 itself. We selected most functions VBP1 had, and list some proteins which have the same functions with VBP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| tubulin binding | GPAA1,STMN2B,NCALD,TBCA,PARK2,PRNP,RITA1,LRRK2,RPS3,BRCA1 |
| protein binding | NDUFS1,CXCL14,ZNHIT6,SH3GLB2,PTPN23,DAPP1,DNASE1,BCL6,ASCC3,RAD9B |
Interacting Protein
VBP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VBP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of VBP1.
PNMA1;UBL7;PFDN4;ORF;PRPF4;Tubb4b;PAN2;TUBA3E;MAP3K3;XRCC6;PIK3R3;Pfdn2
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References
- Snell, CE; Turley, H; et al. Proline-Hydroxylated Hypoxia-Inducible Factor 1 alpha (HIF-1 alpha) Upregulation in Human Tumours. PLOS ONE 9:-(2014).
- Arquier, N; Vigne, P; et al. Analysis of the hypoxia-sensing pathway in Drosophila melanogaster. BIOCHEMICAL JOURNAL 393:471-480(2006).
