Recombinant Human USP25 Protein (P2-L565), GST tagged

• Cat.No.: USP25-0358H
• Product Overview: Recombinant Human GST-TEV-GG-USP21(P2-L565 end) Protein was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: P2-L565
• Description: Deubiquitinates histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A releaves the repression of di- and trimethylation of histone H3 at 'Lys-4', resulting in regulation of transcriptional initiation. Regulates gene expression via histone H2A deubiquitination. Also capable of removing NEDD8 from NEDD8 conjugates but has no effect on Sentrin-1 conjugates. Deubiquitinates BAZ2A/TIP5 leading to its stabilization.
• Form: Liquid
• Endotoxin: < 0.01 EU per μg of the protein
• Purity: 90%
• Stability: Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Supplied as sterile 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
• Shipping: It is shipped out with blue ice.

Gene Information

• Gene Name: USP25 ubiquitin specific peptidase 25 [ Homo sapiens (human) ]
• Official Symbol: USP25
• Synonyms: USP21; ubiquitin-specific protease; USP25; ubiquitin specific peptidase 25
• Gene ID: 29761
• mRNA Refseq: NM_013396
• Protein Refseq: NP_037528
• MIM: 604736
• UniProt ID: Q9UK80