Recombinant Human UPRT Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: UPRT-3595H
• Product Overview: UPRT MS Standard C13 and N15-labeled recombinant protein (NP_659489) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes uracil phosphoribosyltransferase, which catalyzes the conversion of uracil and 5-phosphoribosyl-1-R-diphosphate to uridine monophosphate (UMP). This reaction is an important part of nucleotide metabolism, specifically the pyrimidine salvage pathway. The enzyme localizes to the nucleus and cytoplasm. The protein is a potential target for rational design of drugs to treat parasitic infections and cancer.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 33.8 kDa
• AA Sequence: MATELQCPDSMPCHNQQVNSASTPSPEQLRPGDLILDHAGGNRASRAKVILLTGYAHSSLPAELDSGACGGSSLNSEGNSGSGDSSSYDAPAGNSFLEDCELSRQIGAQLKLLPMNDQIRELQTIIRDKTASRGDFMFSADRLIRLVVEEGLNQLPYKECMVTTPTGYKYEGVKFEKGNCGVSIMRSGEAMEQGLRDCCRSIRIGKILIQSDEETQRAKVYYAKFPPDIYRRKVLLMYPILSTGNTVIEAVKVLIEHGVQPSVIILLSLFSTPHGAKSIIQEFPEITILTTEVHPVAPTHFGQKYFGTDTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: UPRT uracil phosphoribosyltransferase homolog [ Homo sapiens (human) ]
• Official Symbol: UPRT
• Synonyms: UPRT; uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae); uracil phosphoribosyltransferase homolog; DKFZp781E1243; FUR1; MGC23937; RP11 311P8.3; UPRTase; UMP pyrophosphorylase; UPP; RP11-311P8.3
• Gene ID: 139596
• mRNA Refseq: NM_145052
• Protein Refseq: NP_659489
• MIM: 300656
• UniProt ID: Q96BW1