UPRT
-
Official Full Name
uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae) -
Synonyms
UPRT;uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae);uracil phosphoribosyltransferase homolog;Gm774;MGC23937;RGD1564806;RP23-92C4.1;UPP;DKFZp781E1243;FUR1;RP11-311P8.3;UPP_HUMAN;UPRTase;UMP pyrophosphorylase
Recombinant Proteins
- Human
- Cynomolgus
- Zebrafish
- Mouse
- Chicken
- Rhesus macaque
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- His
- Non
- His&GST
- Myc&DDK
- His&Fc&Avi
Involved Pathway
UPRT involved in several pathways and played different roles in them. We selected most pathways UPRT participated on our site, such as Metabolic pathways,Pyrimidine metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with UPRT were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Pyrimidine metabolism | RRM2,ENTPD6,POLE3,POLD4,UCK1,DUT,RRM2B,DTYMK,POLR2EB,NME3 |
| Metabolic pathways | URAH,MMAB,ACSM1,ALDH1A1,CYP4F14,PLA2G4D,NT5C1A,GLUD1A,MTHFD1,ATP6V1B1 |
Protein Function
UPRT has several biochemical functions, for example, protein binding,uridine kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by UPRT itself. We selected most functions UPRT had, and list some proteins which have the same functions with UPRT. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | SLC26A3,HDAC2,RFFL,SWSAP1,CHD8,PPP1R15B,CHID1,SNRPD1,TTF2,IFITM3 |
| uridine kinase activity | UCKL1,CMPK1,UCK2,UCK2B,UCK2A,UCKL1A,UCK1 |
Interacting Protein
UPRT has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UPRT here. Most of them are supplied by our site. Hope this information will be useful for your research of UPRT.
PYROXD1
Resources
Related Services
Related Products
References
- Hasegawa, N; Abei, M; et al. Cyclophosphamide enhances antitumor efficacy of oncolytic adenovirus expressing uracil phosphoribosyltransferase (UPRT) in immunocompetent Syrian hamsters. INTERNATIONAL JOURNAL OF CANCER 133:1479-1488(2013).
- Zaoui, K; Bossow, S; et al. Chemovirotherapy for head and neck squamous cell carcinoma with EGFR-targeted and CD/UPRT-armed oncolytic measles virus. CANCER GENE THERAPY 19:181-191(2012).
