Recombinant Human UDP-glucose pyrophosphorylase 2, His-tagged

• Cat.No.: UGP2-642H
• Product Overview: UGP2, 1-508aa Human, His tag, E.coli

Specification

• Description: UGP2 is an important intermediary in mammalian carbohydrate interconversions. It transfers a glucose moiety from glucose-1-phosphate to MgUTP and forms UDP-glucose and MgPPi. In liver and muscle tissue, UDP-glucose is a direct precursor of glycogen; in lactating mammary gland it is converted to UDP-galactose which is then converted to lactose. Recombinant human UGP2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
• Source: E.coli
• Species: Human
• Tag: His-tag
• Form: Liquid. In Phosphate buffered saline (pH7.4) containing 20% glycerol,1mM DTT
• Molecular Mass: 59.3kDa (531aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMSRFVQD LSKAMSQDGA SQFQEVIRQE LELSVKKELE KILTTASSHE FEHTKKDLDG FRKLFHRFLQ EKGPSVDWGK IQRPPEDSIQ PYEKIKARGL PDNISSVLNK LVVVKLNGGL GTSMGCKGPK SLIGVRNENT FLDLTVQQIE HLNKTYNTDV PLVLMNSFNT DEDTKKILQK YNHCRVKIYT FNQSRYPRIN KESLLPVAKD VSYSGENTEA WYPPGHGDIY ASFYNSGLLD TFIGEGKEYI FVSNIDNLGA TVDLYILNHL MNPPNGKRCE FVMEVTNKTR ADVKGGTLTQ YEGKLRLVEI AQVPKAHVDE FKSVSKFKIF NTNNLWISLA AVKRLQEQNA IDMEIIVNAK TLDGGLNVIQ LETAVGAAIK SFENSLGINV PRSRFLPVKT TSDLLLVMSN LYSLNAGSLT MSEKREFPTV PLVKLGSSFT KVQDYLRRFE SIPDMLELDH LTVSGDVTFG KNVSLKGTVI IIANHGDRID IPPGAVLENK IVSGNLRILD H
• Purity: >85% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25 mg/ml (determined by Bradford assay)
• Protein length: 1-508 a.a.

Gene Information

• Gene Name: UGP2 UDP-glucose pyrophosphorylase 2 [ Homo sapiens ]
• Official Symbol: UGP2
• Synonyms: UGP2; UDP-glucose pyrophosphorylase 2; UDP glucose pyrophosphorylase 1 , UGP1; UTP--glucose-1-phosphate uridylyltransferase; UGPP1; UDPGP; UGPase 2; UDP-glucose diphosphorylase; UDP-glucose pyrophosphorylase 1; UTP-glucose-1-phosphate uridyltransferase; UTP--glucose-1-phosphate uridylyltransferase 2; uridyl diphosphate glucose pyrophosphorylase 2; UDPG; UGP1; UGPP2; UDPGP2; pHC379
• Gene ID: 7360
• mRNA Refseq: NM_001001521
• Protein Refseq: NP_001001521
• MIM: 191760
• UniProt ID: Q16851
• Chromosome Location: 2p14-p13
• Pathway: Amino sugar and nucleotide sugar metabolism, organism-specific biosystem; Amino sugar and nucleotide sugar metabolism, conserved biosystem; Ascorbate biosynthesis, animals, glucose-1P =>ascorbate, organism-specific biosystem; Ascorbate biosynthesis, animals, glucose-1P => ascorbate, conserved biosystem; Biological oxidations, organism-specific biosystem
• Function: UTP:glucose-1-phosphate uridylyltransferase activity; UTP:glucose-1-phosphate uridylyltransferase activity; glucose binding; metal ion binding; nucleotidyltransferase activity; protein binding; pyrimidine ribonucleotide binding; transferase activity