Recombinant Human UBXN11 Protein, MYC/DDK-tagged

• Cat.No.: UBXN11-476H
• Product Overview: Recombinant human UBXN11 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: Myc&DDK
• Description: This gene encodes a protein with a divergent C-terminal UBX domain. The homologous protein in the rat interacts with members of the Rnd subfamily of Rho GTPases at the cell periphery through its C-terminal region. It also interacts with several heterotrimeric G proteins through their G-alpha subunits and promotes Rho GTPase activation. It is proposed to serve a bidirectional role in the promotion and inhibition of Rho activity through upstream signaling pathways. The 3' coding sequence of this gene contains a polymoprhic region of 24 nt tandem repeats. Several transcripts containing between 1.5 and five repeat units have been reported. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 43.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: UBX domain protein 11 [ Homo sapiens ]
• Official Symbol: UBXN11
• Synonyms: COA-1; PP2243; SOC; SOCI; UBXD5
• Gene ID: 91544
• mRNA Refseq: NM_001077262.1
• Protein Refseq: NP_001070730.1
• MIM: 609151
• UniProt ID: Q5T124