Recombinant Human UBE2E2 Protein, His-tagged

• Cat.No.: UBE2E2-311H
• Product Overview: Recombinant Human UBE2E2 Protein is produced by Bacteria expression system. This protein is fused with a His tag.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: Ube2E2 is an E2 enzyme, which is part of the E1, E2, and E3 cascade responsible for ubiquitination of protein substrates. It shares 96% identical amino acid sequence with Ube2E1 and Ube2E3 with the exception of the N-terminal extension that has little in common with the other two E2s. Ube2E2 interacts with ARA54 and RNF8. The RNF8/ Ube2E2 interaction is found to catalyze K48-linked poly-ubiquitination. Ube2E2 may play a role in ubiquitination and subsequent proteasomal degradation of the E3 Ub ligase Parkin.
• Form: 20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol
• Molecular Mass: 22.3 kDa
• Purity: > 90 % by SDS-PAGE
• Storage: Store at -80 centigrade; avoid multiple freeze-thaw cycles.

Gene Information

• Gene Name: UBE2E2 ubiquitin-conjugating enzyme E2E 2 ( Homo sapiens )
• Official Symbol: UBE2E2
• Synonyms: UBCH8
• Gene ID: 7325
• mRNA Refseq: NM_152653
• Protein Refseq: NP_689866
• MIM: 602163
• UniProt ID: Q96LR5