Recombinant Human UBE2D1, His-SUMO-tagged

• Cat.No.: UBE2D1-120H
• Product Overview: Recombinant Human UBE2D1, fused with His6-SUMO tag, was expressed in E.coli.

Specification

• Source: E.coli
• Species: Human
• Tag: His&SUMO
• Molecular Mass: 28,621.5 Da (with Tag)
• Purity: >=95%
• Applications: Identify cognate E2/E3 pairsCharacterize upregulation/downregulation of E2 enzymesBuild poly-ubiquitin chainsCharacterize ubiquitin chain specificity of E2 enzymesAnalyze expression of E2 enzymes
• Storage: Store at -80℃. Avoid repeated freeze/thaw cycles.

Gene Information

• Gene Name: UBE2D1 ubiquitin-conjugating enzyme E2D 1 [ Homo sapiens ]
• Official Symbol: UBE2D1
• Synonyms: UBE2D1; ubiquitin-conjugating enzyme E2D 1; SFT, stimulator of Fe transport , ubiquitin conjugating enzyme E2D 1 (UBC4/5 homolog, yeast); ubiquitin-conjugating enzyme E2 D1; E2(17)KB1; UBC4/5; UBCH5; UbcH5A; UBC4/5 homolog; stimulator of Fe transport; ubiquitin-protein ligase D1; ubiquitin carrier protein D1; ubiquitin-conjugating enzyme E2(17)KB 1; ubiquitin-conjugating enzyme E2-17 kDa 1; ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast); SFT; UBCH5A
• Gene ID: 7321
• mRNA Refseq: NM_001204880
• Protein Refseq: NP_001191809
• MIM: 602961
• UniProt ID: P51668
• Chromosome Location: 10q21.1
• Pathway: APC/C-mediated degradation of cell cycle proteins, organism-specific biosystem; APC/C:Cdc20 mediated degradation of Cyclin B, organism-specific biosystem; APC/C:Cdc20 mediated degradation of Securin, organism-specific biosystem; APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1, organism-specific biosystem; Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem
• Function: ATP binding; acid-amino acid ligase activity; ligase activity; nucleotide binding; protein binding; ubiquitin-protein ligase activity