Recombinant Human TTF1 Protein, His-tagged

• Cat.No.: TTF1-505H
• Product Overview: Recombinant Human TTF1 Protein (Met1-Gly204) with N-His tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• ProteinLength: Met1-Gly204
• Description: This gene encodes a transcription termination factor that is localized to the nucleolus and plays a critical role in ribosomal gene transcription. The encoded protein mediates the termination of RNA polymerase I transcription by binding to Sal box terminator elements downstream of pre-rRNA coding regions. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. This gene shares the symbol/alias 'TFF1' with another gene, NK2 homeobox 1, also known as thyroid transcription factor 1, which plays a role in the regulation of thyroid-specific gene expression.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 27.4 kDa
  Accurate Molecular Mass: \
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: TTF1 transcription termination factor, RNA polymerase I [ Homo sapiens (human) ]
• Official Symbol: TTF1
• Synonyms: TTF1; transcription termination factor, RNA polymerase I; transcription termination factor 1; TTF-1; TTF-I
• Gene ID: 7270
• mRNA Refseq: NM_001205296
• Protein Refseq: NP_001192225
• MIM: 600777
• UniProt ID: Q15361