Recombinant Human TTBK2 protein, His & GST-tagged

• Cat.No.: TTBK2-1312H
• Product Overview: Recombinant Human TTBK2 aa. (Trp21~Thr314 (Accession # Q6IQ55) fused with N-terminal His & GST tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: GST&His
• Protein Length: Trp21~Thr314
• Description: This gene encodes a serine-threonine kinase that putatively phosphorylates tau and tubulin proteins. Mutations in this gene cause spinocerebellar ataxia type 11 (SCA11); a neurodegenerative disease characterized by progressive ataxia and atrophy of the cerebellum and brainstem.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 63.7kDa.
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >90%
• Characteristic: The isoelectric point is 9.5.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: TTBK2 tau tubulin kinase 2 [ Homo sapiens (human) ]
• Official Symbol: TTBK2
• Synonyms: TTBK2; tau tubulin kinase 2; TTBK; SCA11; tau-tubulin kinase 2
• Gene ID: 146057
• mRNA Refseq: NM_173500.3
• Protein Refseq: NP_775771.3
• UniProt ID: Q6IQ55