Recombinant Human TRPV6 Protein, His-tagged

• Cat.No.: TRPV6-349H
• Product Overview: Recombinant Human TRPV6(Met578~Ile725) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: Met578~Ile725
• Description: This gene encodes a member of a family of multipass membrane proteins that functions as calcium channels. The encoded protein contains N-terminal ankyrin repeats, which are required for channel assembly and regulation. Translation initiation for this protein occurs at a non-AUG start codon that is decoded as methionine. This gene is situated next to a closely related gene for transient receptor potential cation channel subfamily V member 5 (TRPV5). This locus has experienced positive selection in non-African populations, resulting in several non-synonymous codon differences among individuals of different genetic backgrounds.
• Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Molecular Mass: 21.2kDa
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
  If bio-activity of the protein is needed, please check active protein.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: TRPV6 transient receptor potential cation channel, subfamily V, member 6 [ Homo sapiens ]
• Official Symbol: TRPV6
• Synonyms: TRPV6; transient receptor potential cation channel, subfamily V, member 6; ECAC2, epithelial calcium channel 2; transient receptor potential cation channel subfamily V member 6; CaT1; caT-L; calcium channel CaT1; calcium transport protein 1; epithelial calcium channel 2; Alu-binding protein with zinc finger domain; epithelial apical membrane calcium transporter/channel CaT1; CAT1; CATL; ZFAB; ECAC2; ABP/ZF; LP6728; HSA277909
• Gene ID: 55503
• mRNA Refseq: NM_018646
• Protein Refseq: NP_061116
• MIM: 606680
• UniProt ID: Q9H1D0