Recombinant Human tRNA Splicing Endonuclease 15 Homolog (S. cerevisiae), His-tagged

• Cat.No.: TSEN15-1787H
• Product Overview: Recombinant humanTSEN15 protein, fused to His-tag at N-terminus, was expressed in E. coli andpurified by using conventional chromatography techniques.

Specification

• Cat. No.: TSEN15-1787H
• Description: TSEN15(tRNA-splicing endonuclease subunit Sen15) belongs to the SEN15 family. tRNAsplicing is a fundamental process required for cell growth and division.SEN15 is a subunit of the tRNA splicing endonuclease. It cleaves pre-tRNA atthe 5" and 3" splice sites to release the intron.
• Concentration: 0.5 mg/ml
• Source: Human
• Host: E.coli
• Form: Suppliedas a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 2mM DTT, 20% glyceroland 200mM NaCl.
• Purity: > 90% by SDS -PAGE
• Sequence: 1-171 amino acids:MGSSHHHHHH SSGLVPRGSH MEERGDSEPT PGCSGLGPDG VRGFGDGGGA PSWAPEDAWM GTHPKYLEMMELDIGDATHV YVAFLVYLDL MESKSWHEVN CVGLPELQLI CLVGTEIEGE GLQTVVPTPI TASLSHNRIREILKASRKLQ GDPDLPMSFT LAIVESDSTI VYYKLTDGFM LPDPQNISLR R
• Molecular Mass: 20.9 kDa(191aa), confirmed by MALDI-TOF.
• Applications: SDS-PAGE
• Storage: Storeat 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg Cor - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.
• OfficialSymbol: TSEN15

Gene Information

• Gene Name: TSEN15 tRNA splicingendonuclease 15 homolog (S. cerevisiae) [ Homo sapiens ]
• Synonyms: TSEN15; tRNA splicing endonuclease 15 homolog (S. cerevisiae);sen15; HsSEN15; SEN15; C1orf19; tRNA-splicing endonuclease subunit Sen15;hsSen15; SEN15 homolog; OTTHUMP00000033516; OTTHUMP00000228759;OTTHUMP00000228760; OTTHUMP00000228761; OTTHUMP00000228762; tRNA-intronendonuclease Sen15; chromosome 1 open reading frame 19
• Gene ID: 116461
• mRNA Refseq: NM_052965
• Protein Refseq: NP_443197
• MIM: 608756
• UniProt ID: Q8WW01
• Chromosome Location: 1q25