TSEN15
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Official Full Name
tRNA splicing endonuclease 15 homolog (S. cerevisiae) -
Overview
tRNA splicing is a fundamental process required for cell growth and division. SEN15 is a subunit of the tRNA splicing endonuclease, which catalyzes the removal of introns, the first step in tRNA splicing (Paushkin et al., 2004 (PubMed 15109492)). -
Synonyms
TSEN15;tRNA splicing endonuclease 15 homolog (S. cerevisiae);C1orf19, chromosome 1 open reading frame 19;tRNA-splicing endonuclease subunit Sen15;Chromosome 1 open reading frame 19;Chromosome 1 open reading frame 19, isoform CRA_c;hsSen15;sen15;SEN15 homolog;tRNA intron endonuclease Sen15;tRNA splicing endonuclease subunit Sen15;OTTHUMP00000033516;OTTHUMP00000228759;OTTHUMP00000228760;OTTHUMP00000228761;OTTHUMP00000228762;tRNA-intron endonuclease Sen15;C1orf19
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- Human
- Mammalian Cell
- E.coli
- HEK293
- HEK293T
- E. coli
- His
- Non
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TSEN15-1787H | Recombinant Human tRNA Splicing Endonuclease 15 Homolog (S. cerevisiae), His-tagged | Human | Human | His |
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| TSEN15-5865Z | Recombinant Zebrafish TSEN15 | Mammalian Cell | Zebrafish | His |
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| TSEN15-693H | Recombinant Human TSEN15 tRNA splicing endonuclease subunit, His-tagged | E.coli | Human | His | 1-171 a.a. |
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| TSEN15-997H | Recombinant Human TSEN15, His-tagged | Human | Human | His |
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| TSEN15-722HCL | Recombinant Human TSEN15 293 Cell Lysate | HEK293 | Human | Non |
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| TSEN15-1562H | Recombinant Human TSEN15 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| TSEN15-2077H | Recombinant Human TSEN15 protein, His-tagged | E. coli | Human | His | 186aa(including fusion tag) |
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| Tsen15-6681M | Recombinant Mouse Tsen15 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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Involved Pathway
TSEN15 involved in several pathways and played different roles in them. We selected most pathways TSEN15 participated on our site, such as Gene Expression,tRNA processing,tRNA processing in the nucleus, which may be useful for your reference. Also, other proteins which involved in the same pathway with TSEN15 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| tRNA processing in the nucleus | TSEN34,TSEN2,XPOT,RPP14,FAM98B,RPP38,POP7,C14orf166,C2orf49,C22orf28 |
| Gene Expression | BRF2,BRF1,C14orf166,AEBP2,GATAD2AB,ZNF354A,ELAVL1,ZNF705A,ZNF543,HNRNPA0L |
| tRNA processing | ALKBH8,KIAA1456,TP53RK,LAGE3,FAM98B,ADAT2,TSEN54,RPP40,QTRT1,ZBTB8OS |
Protein Function
TSEN15 has several biochemical functions, for example, tRNA-intron endonuclease activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TSEN15 itself. We selected most functions TSEN15 had, and list some proteins which have the same functions with TSEN15. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| tRNA-intron endonuclease activity | TSEN34,TSEN2 |
Interacting Protein
TSEN15 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TSEN15 here. Most of them are supplied by our site. Hope this information will be useful for your research of TSEN15.
Clp1;LMO4;NBPF3;EXOSC4
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