Recombinant Human TRIOBP Protein, MYC/DDK-tagged

• Cat.No.: TRIOBP-2638H
• Product Overview: Recombinant Human TRIOBP protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: Myc&DDK
• Description: This gene encodes a protein with an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. The protein interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. The protein also associates with F-actin and stabilizes F-actin structures. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness. Multiple alternatively spliced transcript variants that would encode different isoforms have been found for this gene, however some transcripts may be subject to nonsense-mediated decay (NMD).
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 47.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: TRIOBP TRIO and F-actin binding protein [ Homo sapiens ]
• Official Symbol: TRIOBP
• Synonyms: DFNB28; dJ37E16.4; HRIHFB2122; TAP68; TARA
• Gene ID: 11078
• mRNA Refseq: NM_001039141
• Protein Refseq: NP_001034230
• MIM: 609761
• UniProt ID: Q9H2D6