TRIOBP
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Official Full Name
TRIO and F-actin binding protein -
Overview
This gene encodes a protein with an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. The protein interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. The protein also associates with F-actin and stabilizes F-actin structures. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness. Multiple alternatively spliced transcript variants that would encode different isoforms have been found for this gene, however some transcripts may be subject to nonsense-mediated decay (NMD). -
Synonyms
TRIOBP;TRIO and F-actin binding protein;DFNB28;TRIO and F-actin-binding protein;HRIHFB2122;KIAA1662;Tara;protein Tara;tara-like protein;trio-associated repeat on actin;dJ37E16.4;FLJ39315
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TRIOBP-3419H | Recombinant Human TRIOBP, His-tagged | E.coli | Human | His | C-term-375aa | |
| TRIOBP-2638H | Recombinant Human TRIOBP Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| Triobp-460M | Recombinant Mouse Triobp Protein, MYC/DDK-tagged | HEK293 | Mouse | Myc&DDK |
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Involved Pathway
TRIOBP involved in several pathways and played different roles in them. We selected most pathways TRIOBP participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIOBP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
TRIOBP has several biochemical functions, for example, GTP-Rho binding,actin filament binding,myosin II binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIOBP itself. We selected most functions TRIOBP had, and list some proteins which have the same functions with TRIOBP. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| myosin II binding | GCET2,GSN,GCSAM |
| actin filament binding | ARPC1A,MAP1S,PLDN,PICK1,MYH9,SVILA,TMEM201,FSCN1A,CTNNAL1,WIPF2B |
| ubiquitin protein ligase binding | BCL10,GRIK2,MDM2,FANCL,PRKAR2A,PER1,PARK2,TUBB,DBT,CUL3A |
| GTP-Rho binding | EXOC1,ROCK2B,ROCK1,CDC42EP4,ROCK2A,CDC42EP1,KCTD13,NET1,CDC42EP3,RTKN |
Interacting Protein
TRIOBP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIOBP here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIOBP.
Plk1;POLR1C;VIM;GTF2H1;dppD;hemA;q9wmx2-pro_0000037551;IKBKG
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