Recombinant Human TRIM3 Protein, His-tagged

• Cat.No.: TRIM3-423H
• Product Overview: Recombinant Human TRIM3(Ala2~Arg152) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Description: The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also called the 'RING-B-box-coiled-coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to cytoplasmic filaments. It is similar to a rat protein which is a specific partner for the tail domain of myosin V, a class of myosins which are involved in the targeted transport of organelles. The rat protein can also interact with alpha-actinin-4. Thus it is suggested that this human protein may play a role in myosin V-mediated cargo transport. Alternatively spliced transcript variants encoding the same isoform have been identified.
• Source: E. coli
• Species: Human
• Tag: His
• Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Molecular Mass: 20.3kDa
• Protein length: Ala2~Arg152
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
  If bio-activity of the protein is needed, please check active protein
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Reconstitution: Reconstitute in PBS or others

Gene Information

• Gene Name: TRIM3 tripartite motif containing 3 [ Homo sapiens ]
• Official Symbol: TRIM3
• Synonyms: TRIM3; tripartite motif containing 3; RNF22, tripartite motif containing 3; tripartite motif-containing protein 3; BERP; brain expressed ring finger; HAC1; ring finger protein 22; RNF97; tripartite motif protein TRIM3; RING finger protein 97; tripartite motif-containing 3; brain-expressed RING finger protein; RNF22; FLJ16135
• Gene ID: 10612
• mRNA Refseq: NM_001248006
• Protein Refseq: NP_001234935
• MIM: 605493
• UniProt ID: O75382