Recombinant Human TRIM28 Mutant (K779R) Protein, Myc/DDK-tagged

• Cat.No.: TRIM28-053H
• Product Overview: Purified mutant recombinant protein of Human tripartite motif containing 28 (TRIM28), mutation at((K779R) with a Myc/DDK tag was expressed in HEK293

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: The protein encoded by this gene mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. The protein localizes to the nucleus and is thought to associate with specific chromatin regions. The protein is a member of the tripartite motif family. This tripartite motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region.
• Molecular Mass: 88.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for at least 12 months from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: > 50 μg/mL as determined by microplate Bradford method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Gene Information

• Gene Name: TRIM28 tripartite motif containing 28 [ Homo sapiens (human) ]
• Official Symbol: TRIM28
• Synonyms: TRIM28; tripartite motif containing 28; KAP1; TF1B; RNF96; TIF1B; PPP1R157; transcription intermediary factor 1-beta; E3 SUMO-protein ligase TRIM28; KAP-1; KRAB [Kruppel-associated box domain]-associated protein 1; KRAB-interacting protein 1; KRIP-1; RING finger protein 96; RING-type E3 ubiquitin transferase TIF1-beta; TIF1-beta; nuclear corepressor KAP-1; protein phosphatase 1, regulatory subunit 157; transcriptional intermediary factor 1-beta; EC 2.3.2.27
• Gene ID: 10155
• mRNA Refseq: NM_005762
• Protein Refseq: NP_005753
• MIM: 601742
• UniProt ID: Q13263