Recombinant Human TRIM22 Protein, GST-His-tagged

• Cat.No.: TRIM22-563H
• Product Overview: Recombinant Human TRIM22, transcript variant 1, fused with N-terminal GST and C-terminal His was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His&GST
• Description: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects. Alternative splicing results in multiple transcript variants.
• Form: 25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1% Sarkosyl.
• Molecular Mass: 84.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: TRIM22 tripartite motif containing 22 [ Homo sapiens ]
• Official Symbol: TRIM22
• Synonyms: TRIM22; tripartite motif containing 22; E3 ubiquitin-protein ligase TRIM22; GPSTAF50; RNF94; STAF50; staf-50; RING finger protein 94; tripartite binding motif 22; tripartite motif-containing 22; tripartite motif protein TRIM22; 50 kDa-stimulated trans-acting factor; tripartite motif-containing protein 22; stimulated trans-acting factor (50 kDa)
• Gene ID: 10346
• mRNA Refseq: NM_001199573
• Protein Refseq: NP_001186502
• MIM: 606559
• UniProt ID: Q8IYM9