Recombinant Human TREM1, His-tagged

• Cat.No.: TREM1-30119TH
• Product Overview: Recombinant fragment, corresponding to amino acids 21-200 of Human TREM1 with an amino-terminal hexahistidine tag; 180 amino acids, 20kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 21-200 a.a.
• Description: This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
• Conjugation: HIS
• Tissue specificity: Highly expressed in adult liver, lung and spleen than in corresponding fetal tissue. Also expressed in the lymph node, placenta, spinal cord and heart tissues. Expression is more elevated in peripheral blood leukocytes than in the bone marrow and in norma
• Form: Liquid
• Storage buffer: Preservative: NoneConstituents: 50% Glycerol, PBS
• Storage: Store at -20°C. Stable for 12 months at -20°C
• Sequence Similarities: Contains 1 Ig-like V-type (immunoglobulin-like) domain.

Gene Information

• Gene Name: TREM1 triggering receptor expressed on myeloid cells 1 [ Homo sapiens ]
• Official Symbol: TREM1
• Synonyms: TREM1; triggering receptor expressed on myeloid cells 1; CD354; TREM 1
• Gene ID: 54210
• mRNA Refseq: NM_001242589
• Protein Refseq: NP_001229518
• MIM: 605085
• Uniprot ID: Q9NP99
• Chromosome Location: 6p21.1
• Pathway: Cell surface interactions at the vascular wall, organism-specific biosystem; Hemostasis, organism-specific biosystem
• Function: receptor activity