Recombinant Human transcription factor AP-2 gamma Protein, His&Flag&StrepII tagged

• Cat.No.: TFAP2C-134H
• Product Overview: Recombinant human TFAP2C protein (Q92754) (Ala 94-Asn 206) with a Twin strep tag at the N-terminus and both His, Flag tag at the C-terminus was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: Flag&His&Twin Strep
• Protein Length: 94-206aa
• Description: Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.
• Tag: N-Twin strep and C-His&Flag
• Molecular Mass: 18.8 kDa
• Endotoxin: Less than 1.0 EU/μg by the LAL method.
• Purity: >95% as determined by SDS-PAGE.
• Storage: Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade. It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.
• Reconstitution: Reconstitute at 250 μg/mL in sterile water.

Gene Information

• Gene Name: TFAP2C transcription factor AP-2 gamma [ Homo sapiens (human) ]
• Official Symbol: TFAP2C
• Synonyms: TFAP2C; transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma); transcription factor AP 2 gamma (activating enhancer binding protein 2 gamma); transcription factor AP-2 gamma; AP2 GAMMA; ERF1; estrogen receptor factor 1; hAP 2g; TFAP2G; transcription factor ERF-1; activating enhancer-binding protein 2 gamma; transcription factor AP-2 gamma (activating enhancer-binding protein 2 gamma); hAP-2g; AP2-GAMMA
• Gene ID: 7022
• mRNA Refseq: NM_003222
• Protein Refseq: NP_003213
• MIM: 601602
• UniProt ID: Q92754