TFAP2C
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Official Full Name
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) -
Overview
The protein encoded by this gene is a sequence-specific DNA-binding transcription factor involved in the activation of several developmental genes. The encoded protein can act as either a homodimer or heterodimer with other family members and is induced during retinoic acid-mediated differentiation. It plays a role in the development of the eyes, face, body wall, limbs, and neural tube. -
Synonyms
TFAP2C;transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma);transcription factor AP 2 gamma (activating enhancer binding protein 2 gamma);transcription factor AP-2 gamma;AP2 GAMMA;ERF1;estrogen receptor factor 1;hAP 2g;TFA
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TFAP2C-1875Z | Recombinant Zebrafish TFAP2C | Mammalian Cells | Zebrafish | His |
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| TFAP2C-7347H | Recombinant Human TFAP2C protein(Leu128-Val223), His-tagged | E.coli | Human | His | 128-223 a.a. |
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| TFAP2C-1766HCL | Recombinant Human TFAP2C cell lysate | Human | Non |
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| TFAP2C-134H | Recombinant Human transcription factor AP-2 gamma Protein, His&Flag&StrepII tagged | E.coli | Human | Flag&His&Twin Strep | 94-206aa |
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| Tfap2c-6375M | Recombinant Mouse Tfap2c Protein, Myc/DDK-tagged | HEK293 | Mouse | DDK&Myc |
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Involved Pathway
TFAP2C involved in several pathways and played different roles in them. We selected most pathways TFAP2C participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TFAP2C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
TFAP2C has several biochemical functions, for example, DNA binding,RNA polymerase II distal enhancer sequence-specific DNA binding,RNA polymerase II regulatory region sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TFAP2C itself. We selected most functions TFAP2C had, and list some proteins which have the same functions with TFAP2C. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | HMGA2,FOXJ2,PLSCR1,SIX2,EHF,EBF1,TRP63,NFATC2,NRF1,POU1F1 |
| transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding | HELT,CC2D1B,ESRRA,HES1,SKIL,HHEX,TGIF1,OVOL1,DLX4,ATF7 |
| DNA binding | ESRRA,THRAA,ZFPM1,ZFAND5,SCML2,PAX6B,ZNF311,ZIC5,BHLHE22,TAF4B |
| RNA polymerase II distal enhancer sequence-specific DNA binding | MSC,TAL1,NR5A2,H2AFZ,CDX2,RELA,GZF1,PAX4,ESRRB,PROP1 |
| core promoter binding | PYDC3,NPAS2,HMGA2,MYOD1,E2F3,ELK1,CCAR1,MYBBP1A,NKX3,HDAC2 |
| transcription factor activity, sequence-specific DNA binding | ZNF649,MLLT10,TGIF1,FOXD5,SALL4,TFDP1,VAX2,PLAGL2,HOXC6A,IRF3 |
| RNA polymerase II regulatory region sequence-specific DNA binding | KLF12,ZGLP1,NR1D1,BCL6,ONECUT3,ZBTB11,ZNF548,RUNX3,PRKCBP1L,ATF5A |
| protein binding | PCSK2,POU2AF1,STARD13,SURF1,RBM5,CIR1,ARL3,ATP5A1,SRP14,CDYL2 |
| protein dimerization activity | MITFA,SRFA,MYCB,HNF1A,TFAP2B,HNF1BA,HER4.2,MYCLA,NEUROD6A,HER8A |
Interacting Protein
TFAP2C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TFAP2C here. Most of them are supplied by our site. Hope this information will be useful for your research of TFAP2C.
UBE2I;human_frem2_promoter_region_probe;RARA;CITED2;EYA2;IKBKB;LDLRAD4;LAMA5;ACTN4;NR1I2
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