Recombinant Human TPD52L1, GST-tagged

• Cat.No.: TPD52L1-13702H
• Product Overview: Recombinant Human TPD52L1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• ProteinLength: 1-144a.a.
• Description: This gene encodes a member of the tumor protein D52 (TPD52) family. The encoded protein contains a coiled-coil domain and may form homo- or hetero-dimer with TPD52 family members. The protein is reported to be involved in cell proliferation and calcium signaling. It also interacts with the mitogen-activated protein kinase kinase kinase 5 (MAP3K5/ASK1) and positively regulates MAP3K5-induced apoptosis. Multiple alternatively spliced transcript variants have been observed, but the full-length nature of some variants has not yet been determined.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: TPD52L1 tumor protein D52-like 1 [ Homo sapiens ]
• Official Symbol: TPD52L1
• Synonyms: TPD52L1; tumor protein D52-like 1; tumor protein D53; D53; hD53; MGC8556
• Gene ID: 7164
• mRNA Refseq: NM_001003395
• Protein Refseq: NP_001003395
• MIM: 604069
• UniProt ID: Q16890
• Chromosome Location: 6q22-q23
• Pathway: Clathrin derived vesicle budding, organism-specific biosystem; Golgi Associated Vesicle Biogenesis, organism-specific biosystem; Membrane Trafficking, organism-specific biosystem; trans-Golgi Network Vesicle Budding, organism-specific biosystem
• Function: cysteine-type endopeptidase activator activity involved in apoptotic process; identical protein binding; protein binding; protein heterodimerization activity; protein homodimerization activity