Recombinant Human TOR2A protein, His & T7-tagged

• Cat.No.: TOR2A-1314H
• Product Overview: Recombinant Human TOR2A aa. (Leu49~Ile248 (Accession # Q5JU69) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: His&T7
• Protein Length: Leu49~Ile248
• Description: This gene encodes a member of the AAA family of adenosine triphosphatases with similarity to Clp proteases and heat shock proteins. Alternative splicing at this locus results in the translation of multiple isoforms of the encoded protein, some of which contain salusin peptides in the C-terminal region. These peptides may play roles in hypotension, myocardial growth and the induction of mitogenesis, and may also be involved in the pathogenesis of atherosclerosis. The antimicrobial peptide salusin-beta has antibacterial activity.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 26.3kDa.
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 9.7.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: TOR2A torsin family 2 member A [ Homo sapiens (human) ]
• Official Symbol: TOR2A
• Synonyms: TOR2A; torsin family 2 member A; TORP1; prosalusin; salusin-beta; torsin-2A; torsin-related protein 1
• Gene ID: 27433
• mRNA Refseq: NM_001085347.2
• Protein Refseq: NP_001078816.1
• UniProt ID: Q5JU69