TOR2A
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Official Full Name
torsin family 2, member A -
Overview
This gene encodes a member of the AAA family of adenosine triphosphatases with similarity to Clp proteases and heat shock proteins. Alternative splicing at this locus results in the translation of multiple isoforms of the encoded protein, some of which contain salusin peptides in the C-terminal region. These peptides may play roles in hypotension, myocardial growth and the induction of mitogenesis, and may also be involved in the pathogenesis of atherosclerosis. -
Synonyms
TOR2A;torsin family 2, member A;prosalusin;FLJ14771;TORP1;Prosalusin precursor;Torsin 2A [Precursor];Torsin family 2 member A;Torsin related protein 1;torsin-2A;torsin-related protein 1
Recombinant Proteins
- Human
- Mouse
- Rat
- Zebrafish
- Rhesus macaque
- E.coli
- Mammalian Cells
- HEK293
- His&T7
- His
- His&Fc&Avi
Involved Pathway
TOR2A involved in several pathways and played different roles in them. We selected most pathways TOR2A participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TOR2A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
TOR2A has several biochemical functions, for example, ATP binding,nucleotide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TOR2A itself. We selected most functions TOR2A had, and list some proteins which have the same functions with TOR2A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| nucleotide binding | IMPDH2,GNA11A,MARF1,HNRNPH1,Akap17b,RHOAC,LMTK2,RERGLA,PKM,NT5E |
| ATP binding | HK1,ACTG2,LIG1,ASNA1,SNRK,CDK11B,RLN1,DDX42,TAP1,PI4KB |
Interacting Protein
TOR2A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TOR2A here. Most of them are supplied by our site. Hope this information will be useful for your research of TOR2A.
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References
- Konakova, M; Pulst, SM; et al. Immunocytochemical characterization of torsin proteins in mouse brain. BRAIN RESEARCH 922:1-8(2001).
