Recombinant Human TMX1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: TMX1-4044H
• Product Overview: TMX1 MS Standard C13 and N15-labeled recombinant protein (NP_110382) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and one transmembrane domain. Unlike most members of this gene family, it lacks a C-terminal ER-retention sequence. The mature membrane-bound protein can both oxidize and reduce disulfide bonds and acts selectively on membrane-associated polypeptides.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 31.8 kDa
• AA Sequence: MAPSGSLAVPLAVMVPLLWGAPWTHGRRSNVRVITDENWRELLEGDWMIEFYAPWCPACQNLQPEWESFAEWGEDLEVNIAKVDVTEQPGLSGRFIINALPTIYHCKDGEFRRYQGPRTKKDFINFISDKEWKSIEPVSSWFGPGSVLMSSMSALFQLSMWIRTCHNYFIEDLGLPVWGSYTVFALATLFSGLLLGLCMIFVADCLCPSKRRRPQPYPYPSKKLLSESAQPLKKVEEEQEADEEDVSEEEAESKEGTNKDFPQNAIRQRSLGPSLATDKSTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: TMX1 thioredoxin-related transmembrane protein 1 [ Homo sapiens (human) ]
• Official Symbol: TMX1
• Synonyms: TMX1; thioredoxin-related transmembrane protein 1; thioredoxin domain containing, thioredoxin domain containing 1, thioredoxin domain containing, TXNDC, TXNDC1; PDIA11; protein disulfide isomerase family A; member 11; thioredoxin related transmembrane protein; TMX; thioredoxin domain containing 1; transmembrane Trx-related protein; thioredoxin domain-containing protein 1; protein disulfide isomerase family A, member 11; TXNDC; TXNDC1; DKFZp564E1962
• Gene ID: 81542
• mRNA Refseq: NM_030755
• Protein Refseq: NP_110382
• MIM: 610527
• UniProt ID: Q9H3N1