Recombinant Human TMPRSS4, MYC/DDK-tagged

• Cat.No.: TMPRSS4-3839H
• Product Overview: Recombinant Human TMPRSS4, fused with C-terminal MYC/DDK, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the serine protease family. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified as a gene overexpressed in pancreatic carcinoma. The encoded protein is membrane bound with a N-terminal anchor sequence and a glycosylated extracellular region containing the serine protease domain. Multiple transcript variants encoding different isoforms have been found for this gene.
• Source: HEK293 cells
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 48 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: TMPRSS4 transmembrane protease, serine 4 [ Homo sapiens (human) ]
• Official Symbol: TMPRSS4
• Synonyms: TMPRSS4; CAPH2; MT-SP2; TMPRSS3; transmembrane protease, serine 4; transmembrane protease serine 4; channel-activating protease 2; membrane-type serine protease 2; transmembrane serine protease 3; type II membrane serine protease
• Gene ID: 56649
• mRNA Refseq: NM_019894
• Protein Refseq: NP_063947
• MIM: 606565
• UniProt ID: Q9NRS4
• Chromosome Location: 11q23.3
• Pathway: Influenza A
• Function: scavenger receptor activity; serine-type endopeptidase activity