TMPRSS4
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Official Full Name
transmembrane protease, serine 4 -
Overview
This gene encodes a member of the serine protease family. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified as a gene overexpressed in pancreatic carcinoma. The encoded protein is membrane bound with a N-terminal anchor sequence and a glycosylated extracellular region containing the serine protease domain. Multiple transcript variants encoding different isoforms have been found for this gene. -
Synonyms
TMPRSS4;transmembrane protease, serine 4;transmembrane protease serine 4;membrane type serine protease 2;MT SP2;TMPRSS3;transmembrane serine protease 3;type II membrane serine protease;UNQ776/PRO1570;TMPRSS 4;OTTHUMP00000225915;OTTHUMP00000225916;OTTHUMP00000225917;OTTHUMP00000225918;OTTHUMP00000225921;OTTHUMP00000233153;channel-activating protease 2;membrane-type serine protease 2;CAPH2;MT-SP2
Recombinant Proteins
- Human
- Cynomolgus
- Mouse
- E.coli
- HEK293
- Mammalian Cell
- HEK293T
- Mamanlian cells
- GST
- His
- His&Avi
- Myc&DDK
- Non
- His&SUMO
- Flag
- His&Myc
- His&Fc&Avi
Involved Pathway
TMPRSS4 involved in several pathways and played different roles in them. We selected most pathways TMPRSS4 participated on our site, such as Influenza A, which may be useful for your reference. Also, other proteins which involved in the same pathway with TMPRSS4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Influenza A | RAF1,STAT1,CCL5,HLA-DPB1,IKBKB,HLA-DMB,IFNA5,OAS1,RNASEL,KPNA1 |
Protein Function
TMPRSS4 has several biochemical functions, for example, protein binding,scavenger receptor activity,serine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TMPRSS4 itself. We selected most functions TMPRSS4 had, and list some proteins which have the same functions with TMPRSS4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| serine-type endopeptidase activity | PRSS2,KLK1B3,RHBDD1,KLK6,PRSS12,HTRA1B,PRSS59.1,Acr,MCPT8,F9B |
| scavenger receptor activity | PGBD1,LOXL3A,TMPRSS2,ENPP1,SCART1,SRCRB4D,GM106,TINAGL1,PRSS12,HHIPL1 |
| protein binding | TAB1,TIGIT,RPS2,CCT2,MITD1,C1orf105,BLOC1S6,RYBP,ITSN2,C19orf47 |
Interacting Protein
TMPRSS4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TMPRSS4 here. Most of them are supplied by our site. Hope this information will be useful for your research of TMPRSS4.
CCDC155;TMEM79
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