Recombinant Human TLE3 Protein, DDK-tagged

• Cat.No.: TLE3-091H
• Product Overview: Recombinant Human TLE3, transcript variant 1, fused with DDK tag at C-terminal was expressed in Sf9 cells.

Specification

• Species: Human
• Source: Sf9 Cells
• Tag: Flag
• Description: This gene encodes a transcriptional co-repressor protein that belongs to the transducin-like enhancer family of proteins. The members of this family function in the Notch signaling pathway that regulates determination of cell fate during development. Expression of this gene has been associated with a favorable outcome to chemotherapy with taxanes for ovarian carcinoma. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
• Form: 50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol. Store at -80 centigrade. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
• Molecular Mass: 83.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: TLE3 transducin like enhancer of split 3 [ Homo sapiens (human) ]
• Official Symbol: TLE3
• Synonyms: ESG; ESG3; GRG3; HsT18976; TLE3
• Gene ID: 7090
• mRNA Refseq: NM_001105192
• Protein Refseq: NP_001098662
• MIM: 600190
• UniProt ID: Q04726