Recombinant Human TINAG Protein, His-tagged

• Cat.No.: TINAG-413H
• Product Overview: Recombinant Human TINAG Protein (Met1-Pro476) with N-His tag was expressed in E. coli.

Specification

• Description: This gene encodes a glycoprotein that is restricted within the kidney to the basement membranes underlying the epithelium of Bowman's capsule and proximal and distal tubules. Autoantibodies against this protein are found in sera of patients with tubulointerstital nephritis, membranous nephropathy and anti-glomerular basement membrane nephritis. Ontogeny studies suggest that the expression of this antigen is developmentally regulated in a precise spatial and temporal pattern throughout nephrogenesis.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 58.3 kDa
  Accurate Molecular Mass: 58&15 kDa
• Protein length: Met1-Pro476
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1 mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: TINAG tubulointerstitial nephritis antigen [ Homo sapiens (human) ]
• Official Symbol: TINAG
• Synonyms: TINAG; tubulointerstitial nephritis antigen; TIN-AG
• Gene ID: 27283
• mRNA Refseq: NM_014464
• Protein Refseq: NP_055279
• MIM: 606749
• UniProt ID: Q9UJW2